Molbank 2005, M418 |
3-(2,5-Bis-hexyloxy-4-iodo-phenylethynyl)-[1,10]-phenanthroline
Davood Habibi
Department of Chemistry, Faculty of Sciences, Bu
Hamedan, Iran.
Code:6517838683.
e-mail: [email protected]
Received:
Keywords: 1,4-bis-hexyloxy-2,5-diiodobenzene, Sonogashira procedure, phenanthroline
The experimental
procedure follows a protocol developed by Sonogashira
[1]. All reactions were carried out under the atmosphere of dry argon by using
standard Schlenk tube techniques.
To a mixture of
3-ethynyl-[1,10]-phenanthroline
[2,3] (306 mg, 1.5 mmol) and
1,4-bis-hexyloxy-2,5-diiodobenzene [4-6] (3.975 g, 7.5 mmol)
in dry benzene (25 mL), and triethyl
amine (10 mL), were added CuI
(28.6 mg, 0.15 mmol), and [PdCl2(PPh3)2]
(52.6 mg, 0.075 mmol). The reaction mixture was kept
at 80 oC for 24h while stirring vigorously
and monitored with mass spectrometer to see the formation of the desired
product. After removal of the solvent, the residue was washed with aqueous
potassium cyanide (2%, 30 mL) and distilled water
(100 mL), and purified by column chromatography (SiO2,
CHCl3) to collect 3-(2,5-bis-hexyloxy-4-iodo-phenylethynyl)-[1,10]-phenanthroline (227.5 mg, 0.375 mmol,
25%).
Melting Point: > 300 ¡ãC.
IR (KBr, cm-1): 3205, 2202, 1590, 1477, 1415, 1261, 1202, 1095, 1053, 940, 818, 729.
1H-NMR (200 MHz, d6-acetone): ¦Ä= 0.95 (6H, 2CH3); 1.3 (12H, 6CH2); 1.7 (4H, 2CH2); 4.0 (4H, 2CH2); 6.6 (1H, 8'-H); 7.0 (1H, 5'-H); 7.25 (1H, 8-H); 7.4 (1H, 5-H); 7.7 (1H, 6-H); 8.0 (1H, 7-H); 8.2 (1H, 4-H); 8.8 (1H, 9-H); 9.0 (1-H, 2-H).
Elemental Analysis: Calculated for C32H35IN2O2: C, 63.37%; H, 5.82%, N, 4.62%. Found: C, 63.5%; H, 6.0%, N, 4.50%.
Acknowledgements
The author gratefully acknowledges
the financial supports from the Bu Ali Sina
University,
References
1.
Sonogashira, K.; Tohda, Y.; Hagihara, N. Tetrahedron Lett. 1975,
4467.
2. Michel, C.;
Habibi, D.; Schmittel, M., Molecules, 2001, M224.
3. Michel, C.;
Habibi, D.; Schmittel, M., Molecules, 2001, M225.
4. Giesa, R.;
Schulz, R. C., Makromol. Chem., 1990,
191, 857.
5. Weder, C.; Wrighton,
M. S., Macromolecules, 1996, 29, 5157.
6. Swager, T. M.; Gil, C. J.; Wrighton, M. S., J. Phys. Chem., 1995, 99, 4886.
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