Molbank 2008, M576
molbank
ISSN 1422-8599
www.mdpi.org/molbank
Short Note
Abdelouahhab El Rhazi,
Abdesselam Baouid,* Said
Elhazazi, Aicha Boudina and
Mohamed Essaber
Laboratoire de Chimie
Moléculaire, Equipe de Chimie des Hétérocycles et Valorisation des Extraits des Plantes, Département de Chimie, Faculté des Sciences-Semlalia, Université Cadi Ayyad, B.P 2390, 40001 Marrakech, Maroc.
E-mail: [email protected], [email protected],
[email protected], [email protected], [email protected]
* Author to whom correspondence should be addressed.
Received: 23 July 2008 / Accepted: 27 August 2008 / Published: 4 September 2008
Keywords: 1,5-Benzodiazepin-2-one, dimethylformamide-dimethylacetal.
Melting point: 224-225 °C (Diethyl ether).
MS (m/z, %): 292 ([M+H]+, 100%).
1H NMR (CDCl3,
400 MHz), d(ppm): 2.55 (s, 6H, (CH3)2N),
2.80 (s,
13C NMR (CDCl3, 100 MHz), d(ppm): 43.50 (N(CH3)2), 98.02 (C-3), 121.47, 124.59, 127.34, 128.13, 128.67, 128.89, 130.65, 131.78, 141.86 (C-Ar), 151.18 (C=CH-N(CH3)2), 167.40 (C-4), 178.57 (C=O).
1.
Solomko, Z.F.; Proshkina,
V.N.; Bozhanova, N.Ya.; Loban, S.V.; Babichenko, L.N. Vilsmeier reaction with
4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one. Khim.
Geterosikl. Soedin. 1984, 223.
2.
Ried, W.; Stahlhofen, P.
Über heterocyclische siebenringsysteme, vii der reaktionsverlauf zwischen
o-phenylendiamin und alkyliden-brenztraubensäuren. Chem. Ber. 1957, 90, 828.
3.
Nardi, D.; Tajana, A.;
Rossi, S. J. Heterocyclic compounds from 3,3-dimercapto-1-aryl-2-propen-1-ones.
Note 1. 4-aryl-1,3-dihydro-2H-1,5-benzodiazepine-2-thiones. Heterocyc.
Chem. 1973, 10, 815.
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