Combinatorial Chemistry. By Willi Bannwarth and Eduard Felder (eds.). Wiley-VCH, Weinheim. 2000. 430 pages. Hardcover. 268.- DM / 137.03 EUR / 238.- SFR. ISBN 3-527-30186-0
Received: 22 December 2000
As we enter the new millennium, combinatorial chemistry
is providing significant impetus to new innovations in synthetic chemistry.
Combinatorial chemistry has rapidly become the rising star among research
methods, allowing scientists to efficiently test the feasibility of a multitude
of new compounds.
The pursuit of new drugs is but one challenging field in which these
combinatorial methods are particularly advantageous, helping researchers
meet the modern-day demands of a highly competitive environment.
This book emphasises that modern combinatorial synthesis is possible
not only in the solid phase, but also in solutions. Moreover, it discusses
computer-assisted methods as well as the apparatus and instrumentation
required for the combinatorial method. Successful and experienced researchers
in the leading pharmaceutical companies and most renowned research institutes
offer a solid insight and perspective into this diverse field.
A 'must' for every scientist in the area of pharmaceutical research.
*Editor's Note: The brief summary and the contents of the books are reported as provided by the author or the publishers. Authors and publishers are encouraged to send review copies of their recent books of potential interest to readers of Molecules to the Editor-in-Chief (Dr. Shu-Kun Lin, MDPI, Saengergasse 25, CH-4054 Basel, Switzerland. Tel. +41 79 322 3379, Fax +41 61 302 8918, E-mail: [email protected]). Some books will be offered to the scholarly community for the purpose of preparing full-length reviews.1. General Introduction
2. Combinatorial Chemistry in Solution
2.1 Introduction
2.2 Multicomponent Condensations
2.3 Purification in High Speed Solution-Phase Synthesis
3. Solid-Phase Chemistry
3.1 Linkers for Solid-Phase Organic Synthesis and Combinatorial Approaches on Solid Support
3.2 Cyclative Cleavage: A Versatile Concept in Solid-Phase Organic Chemistry
3.3 C-C Bond Forming Reactions
3.4 Combinatorial Synthesis of Heterocycles
4. Polymer Supported Reagents: Preparation and Use in Parallel Organic Synthesis
5. Encoding Strategies for Combinatorial Chemistry
6. Devices for Combinatorial Synthesis
7. Computer-Assisted Library Design
© 2000 by MDPI (http://www.mdpi.org).