Review
manuscripts: Before writing their manuscripts, potential authors of
review articles
should forward the title and a short abstract to
[email protected],
with
copy to the Guest Editors.
We will then provide feedback on the suitability of the topic.
Seung
Ho Lee, Jong-Keun Son, Byeong Seon Jeong, Tae-Cheon Jeong, Hyeon Wook
Chang, Eung-Seok Lee and Yurngdong Jahng *
College of Pharmacy, Yeungnam University, Gyeongsan 712-749 Korea
* Author to whom correspondence should be addressed; E-mail:
[email protected]
Received: 1 January 2008; in revised
form 1 February 2008 / Accepted: 2 February 2008 / Published: 6
February 2008
Review: Progress in the Studies on Rutaecarpine
Molecules
2008, 13, 272-300
(PDF
format 1116 K)
Javier Palazón 1,*, Arturo Navarro-Ocaña 2, Liliana Hernandez-Vazquez 1 and Mohammad Hossein Mirjalili 31
Laboratori de Fisiologia Vegetal, Facultat de Farmacia, Universitat de
Barcelona, Avda Diagonal 643, E-08028, Barcelona, Spain; E-mail:
[email protected]2 Departamento de Alimentos y
Biotecnologia, Facultad de Química, Universidad Nacional Autónoma de
México, México DF, México; E-mail:
[email protected]3 Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Evin, Tehran, Iran; E-mail:
[email protected]* Author to whom correspondence should be addressed; E-mail:
[email protected].
Received: 3 June 2008; in revised form: 12 August 2008 / Accepted: 14 August 2008 / Published: 18 August 2008Review: Application of Metabolic Engineering to the Production of ScopolamineMolecules
2008,
13, 1722-1742 (PDF format 1422 K); DOI:
10.3390/molecules13081722
László F. SzabóDepartment of Organic Chemistry, Semmelweis University, Hőgyes utca 7, H-1092 Budapest, Hungary; E-mail:
[email protected]Received: 5 August 2008; in revised form: 24 August 2008 / Accepted: 26 August 2008 / Published: 27 August 2008Review: Rigorous Biogenetic Network for a Group of Indole Alkaloids Derived from StrictosidineMolecules
2008,
13, 1875-1896 (PDF format 414 K); DOI:
10.3390/molecules13081875
Type of the paper: Review
Tentative Title: Analysis of Isoquinoline Alkaloids by
Liquid Chromatography Methods
Author: Monika Waskmundzka-Hajnos
E-mail:
[email protected]
Type of the paper: Review
Tentative Title: Selective Accounts on Bioactive Alkaloids
from Marine Organisms
Author: Phil Crews
E-mail:
[email protected]
Department of Chemistry, University of California, 1156 High Street,
Santa Cruz, CA 95064, USA
http://chemistry.ucsc.edu/faculty/crews.html
Molecules Manuscript ID: alkaloids-20071203-Sultana-pk
Type of the paper: Review
Title:
Pharmacological and spectral
studies on Quinoline Alkaloids from Skimmia
laureola
Authors: Nighat Sultana* and Ather Ata
E-mail:
[email protected]
Abstract: This review covers the introduction, pharmacological
activities, the spectral features and biosynthesis of quinoline
alkaloids in Skimmia laureola. The aim of the present study is to
describe the pharmacological and spectral features of constituents of
Skimmia laureola. The pharmacological properties of quinoline alkaloids
have been investigated to a limited degree and as a result evidence of
cytotoxic, phototoxic, mutagenic, antibacterial and anti-viral (HIV)
activity has been observed. Individual presentations on various aspects
of quinoline alkaloids have also appeared as book chapters or articles
in journals. These constituents have attracted considerable interest
due to their biological activity but only few publications have
appeared on the spectral features of chemical constituents of the plant
S. laureola.
Molecules Manuscript ID: alkaloids-20071204-Andraos-ca
Type of the paper: Review
Title:
A Critical Appraisal of
Various Total Syntheses of the Woodward Alkaloids with Respect to Green Chemistry Metrics
Authors: John Andraos
York University, Department of Chemistry, 4700 Keele Street, Toronto,
ON M3J 1P3, CANADA
E-mail:
[email protected]
Abstract: This review gives a thorough up-to-date green metrics
evaluation of the state-of-the-art in the achievement of total
syntheses of the celebrated Woodward alkaloids quinine, lysergic acid,
morphine, strychnine, reserpine, and colchicine by various research
groups with respect to material efficiency and synthesis strategy
parameters. In particular, synthesis plans are evaluated with respect
to atom economy (AE), reaction mass efficiency (RME), molecular weight
building up parameter, degree of convergence and degree of asymmetry
using the synthesis tree algorithm. Simple template spreadsheet
programs are introduced to calculate these parameters for linear and
convergent plans using number of steps, number of input reagents,
reaction yields and molecular weights of reagents, intermediates, and
byproducts as the only input data. New concepts are introduced in this
work which give a deeper understanding of synthesis strategy and
design, namely hypsicity (oxidation level)
index, structure mapping, and fraction of sacrificial reagents.
Key references: Andraos, J. Org. Process Res. Develop. 2005, 9, 149
Andraos, J. Org. Process Res. Develop. 2005, 9, 404
Andraos, J. Org. Process Res. Develop. 2006, 10, 212
Andraos, J. Application of Green Metrics Analysis to Chemical Reactions
and
Synthesis Plans in Green Chemistry Metrics (A. Lapkin and D.C.
Constable, eds.)
Blackwell Scientific: Oxford, in press
Research
papers
Beata Jasiewicz
Faculty of Chemistry, A. Mickiewicz University, Grunwaldzka 6, 60-780
Poznań, Poland; E-mail: [email protected]
Received: 4 December 2007 / Accepted:
30 December 2007 / Published: 9 January 2008
Communication: NMR Spectra of Sparteine N1-oxide and
α-Isosparteine N-oxide
Molecules
2008, 13, 3-10
(PDF
format 77 K)
Jae Joon Lee 1,
Chun Mei Jin 1, Young Kyoon Kim 2,
Shi Yong Ryu 3, Sung Cil Lim 1
and Myung Koo Lee 1,*
1 College of Pharmacy and Research Center for Bioresource and Health,
Chungbuk National University, 12, Gaeshin-dong, Heungduk-gu, Cheongju
361-763, Korea; E-mail:
[email protected] (Jae Joon Lee);
[email protected] (Chun Mei Jin);
[email protected] (Sung Cil Lim)
2 College of Forest Science, Kookmin University, Seoul 136-702, Korea;
E-mail:
[email protected] (Young Kyoon Kim)
3 Korea Research Institute of Chemical Technology, Taejeon 305-606,
Korea; E-mail:
[email protected] (Shi Yong Ryu)
* Author to whom correspondence should be addressed. E-mail:
[email protected]; Tel: +82-43-262-2822, Fax: +82-43-276-2754.
Received: 30 January 2008; in revised
form: 22 February 2008 / Accepted: 25 February 2008 / Published: 27
February 2008
Full Paper: Effects of Anonaine on Dopamine
Biosynthesis and L-DOPA-Induced Cytotoxicity in PC12 Cells
Molecules
2008, 13, 475-487
(PDF
format 132 K)
Ernesto Fattorusso, Adriana Romano, Fernando Scala and Orazio Taglialatela-Scafati *Dipartimento
di Chimica delle Sostanze Naturali, Università di Napoli “Federico II”,
Via D. Montesano 49, 80131 Napoli, Italy.; E-mails:
[email protected];
[email protected];
[email protected]* Author to whom correspondence should be addressed. Tel. +39-081678509; E-mail:
[email protected]Received: 25 June 2008 / Accepted: 16 July 2008 / Published: 17 July 2008Article: Simplexidine, a 4-Alkylpyridinium Alkaloid from the Caribbean Sponge Plakortis simplex
Molecules
2008, 13, 1465-1471
(PDF
format 206 K); DOI:
10.3390/molecules13071465 Alexandra CH F Sawaya 1,2,*, Ilka Nacif Abreu 3,4, Nathalia Luiza Andreazza 3, Marcos N. Eberlin 1 and Paulo Mazzafera 31 ThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, State University of Campinas - UNICAMP, Campinas, SP, Brazil
2 Bandeirante University of São Paulo, UNIBAN, São Paulo, SP, Brazil
3 Department of Plant Physiology, Institute of Biology, State University of Campinas - UNICAMP, Campinas, SP, Brazil
4 Umeå Plant Science Centre – Umeå – Sweden
*
Author to whom correspondence should be addressed; e-mail:
[email protected]; UNIBAN,Rua Maria Cândida 1813, Vila Guilheme,
São Paulo, CEP 02071-013, SP, Brazil, Phone: +55-11-2967-9147; Fax:
+55-11-4412-5871.
Received: 28 May 2008; in revised form: 22 June 2008 / Accepted: 18 July 2008 / Published: 30 July 2008
Article: HPLC-ESI-MS/MS of Imidazole Alkaloids in Pilocarpus microphyllus
Molecules
2008, 13, 1518-1529
(PDF
format 335 K); DOI:
10.3390/molecules13071518
Sabira Begum*,
Syed Nawazish Ali, Farhat, Syed Imran Hassan and Bina S. Siddiqui
H.
E. J. Research Institute of Chemistry, International Center for
Chemical and Biological Sciences, University of Karachi, Karachi-75270,
Pakistan; E-mails:
[email protected] (Syed Nawazish Ali);
[email protected] (Farhat);
[email protected] (Syed Imran
Hassan);
[email protected] (Bina S. Siddiqui)
* Author to whom
correspondence should be addressed; E-mail:
[email protected],
[email protected]; Tel.: +92-21-4824901; Fax:
+92-21-4819018/4819019
Received: 6 May 2008; in revised
form: 24 June 2008 / Accepted: 23 July 2008 / Published: 6 August 2008
Article: A
Simple, Rapid and Mild One Pot Synthesis of Benzene Ring Acylated and
Demethylated Analogues of Harmine under Solvent-free Conditions
Molecules 2008, 13, 1584-1598 (PDF format 217 K); DOI:
10.3390/molecules13081584
Type of the paper: Article
Tentative Title:
Chemptothecinoids
from the seeds of Nothapodytes foetida
Author: Dr. Fang-Rong Chang, Professor / Director, Graduate Institute
of Natural Products, School of Pharmacy
Kaohsiung Medical University, Kaohsiung 807, Taiwan
Tel: +886-7-3121101p2162, Fax: +886-7-3114773
E-mail:
[email protected]
http://www.kmu.edu.tw/%7Ecpharm/faculty/upload/179.pdf
Type of the Paper: Article
Tentative Title:
Idenfication of
Atropine in Transgenic Cannabis Roots by EC-CG/MS
Author: Antonio Segura
E-mail:
[email protected]
Dr. Antonio Segura Carretero
Profesor Titular
Dpto Química Analítica (Analytical Chemistry)
Facultad de Ciencias. Universidad de Granada (Faculty of Sciences,
University of Granada)
C/Fuentenueva s/n
18071 Granada (Spain)
http://www.ugr.es/local/ansegura
Alkaloids papers published
in Molecules before
Evangelia N. Tzanetou 1,
Konstantinos M. Kasiotis 1, Prokopios Magiatis 2
and
Serkos A. Haroutounian 1,*
1 Chemistry Laboratory, Agricultural University of Athens, Iera odos
75, Athens 11855, Greece
2 Faculty of Pharmacy, Laboratory of Pharmacognosy and Natural Products
Chemistry, University of Athens, Panepistimiopolis Zografou, Athens
15771, Greece
* Author to whom correspondence should be addressed; E-mail:
[email protected]
Received: 13 March 2007;
in revised
form: 25 March 2007 / Accepted: 27 March 2007 / Published: 10 April 2007
Full Paper: Synthesis of (R)-Dihydropyridones
as Key
Intermediates for an Efficient Access to Piperidine Alkaloids
Molecules
2007,
12,
735-744
(PDF
format 99 K)
Juan M. Ruiz, María M.
Afonso
and J. Antonio Palenzuela*
Instituto Universitario de Bio-Orgánica “Antonio
González”, Departamento de Química Orgánica,
Universidad de La Laguna, 38206 La Laguna, Tenerife, Spain
* Author to whom correspondence should be addressed. E-mail:
[email protected]
Received: 25 January
2007; in revised
form: 13 February 2007 / Accepted: 13 February 2007 / Published: 19
February 2007
Full Paper:
Synthesis of
2,5-Disubstituted
Octahydroquinolin-4-ones via an Intramolecular Hetero Diels-Alder
Reaction
Molecules 2007,
12, 194-204 (PDF
format 79 K)
Çigdem Yolacan 1,
Emine Bagdatli 1, Nüket Öcal 1,*
and Dieter E. Kaufmann 2,*
1 Yıldız Technical University, Faculty of Art and Sciences, Department
of Chemistry, Davutpasa Campus, 34210, Istanbul, Turkey
2 Clausthal University of Technology, Institute of Organic Chemistry,
Leibnizstr. 6, D-38678 Clausthal-Zellerfeld, Germany
* Authors to whom correspondence may be addressed; e-mails:
[email protected];
[email protected]
Full Paper: Epibatidine Alkaloid
Chemistry:
5.
Domino-Heck Reactions of Azabicyclic and Tricyclic Systems
Molecules 2006,
11, 603-614 (PDF
format 77 K)
I. Southwell
NSW Department of Primary Industries, Wollongbar
Agricultural Institute, Australia
E-mail:
[email protected]
Review:
25
Years of Natural Product R&D with New South Wales Agriculture
Molecules 2005, 10, 1232-1241
(PDF format 219 K)
Haruaki Ishiyama, Masashi Tsuda, Tadashi
Endo and Jun’ichi Kobayashi*
Graduate
School of Pharmaceutical
Sciences, Hokkaido University, Sapporo 060-0812, Japan. Tel:
(+81) 11-706-4985, Fax: (+81) 11-706-4989.
* Author to
whom correspondence should be
addressed; e-mail:
[email protected].
Asymmetric
Synthesis of
Double Bond Isomers of the Structure Proposed for Pyrinodemin A and
Indication
of Its Structural Revision
Molecules 2005,
10, 312–316
(PDF format 192 K)
Rafael Chinchilla,
Patricia Mazón and Carmen Nájera*
Departamento de Química
Orgánica and
Instituto de Síntesis Orgánica (ISO), Universidad de
Alicante, Apdo. 99, 03080 Alicante, Spain. Tel.: (+34) 965 903728, Fax:
(+34) 965 903549.
*Author to whom correspondence should be addressed; E-mail: [email protected]
Polymer-Supported Cinchona
Alkaloid-Derived Ammonium
Salts as Recoverable Phase-Transfer Catalysts for the
Asymmetric Synthesis of α-Amino Acids
Molecules 2004,
9, 349-364 (PDF format 220 K)
Gy. Hajós a,*, Zs. Riedl a, G.
Timári a,&,
P. Mátyus b, B. U. W. Maes c and G. L.
F.
Lemière c
a Institute of Chemistry, Chemical Research Center,
Hungarian
Academy of Sciences, Pusztaszeri út 59, H-1025 Budapest,
Hungary.
b Institute of Organic Chemistry, Semmelweis
University,
H-1092 Budapest, Hogyes E. u. 7., Hungary.
c Department of Chemistry, University of Antwerp
(RUCA),
Groenenborgerlaan 171, B-2020, Antwerpen, Belgium.
& Present address: CHINOIN Pharmaceutical Works
Co.
Ltd, H-1325 Budapest, PO Box 110, Hungary.
* Author to whom correspondence should be addressed.
E-mail:
[email protected]
Synthesis of New Polyfused
Heterocycles
of Biological Importance by Means of Pd(0) Catalysis
Molecules 2003,
8, 480-487 (PDF format 149 K)
I. Ugi 1,*,
B. Werner 1 and
A.
Dömling 2
1 Institute of Organic Chemistry and Biochemistry,
Technical
University of München, D-85747 Garching, Germany, Tel.
+49-89-289-13229,
Fax +49-89-289-13249.
2 Morphochem A.G., Gmunder Street 37 – 37a, D-81379
München,
Germany, Tel. +49-89-78005-0 Fax +49-89-78005-555, e-mail:
[email protected]
†Dedicated to the memory of Prof. Wang Yu
* Author to whom correspondence should be addressed:
e-mail:
[email protected]
Invited Lecture and Review: The Chemistry
of Isocyanides, their MultiComponent Reactions and their Libraries†
Molecules 2003,
8, 53-66 (PDF format 299 K)
Also see the papers
alkaloids
papers publisehd in Marine Drugs.
Webmaster:
Dr. Shu-Kun
Lin, E-mail:
[email protected]
Last update: 10 September 2008